#JQuery isn't the right tool for building application interfaces. We need a framework that provides 2 way binding. After this release, we will seriously look into #ReactJS and #AngularJS. Yes I know about the opposite nature of them.
I'd prefer #ReactJS over #AngularJS. Maybe web components (http://webcomponents.org/) would be best though. Its just a polyfill right now and as the standard gets solidified and implemented in the browsers we won't even need the polyfill. That way we won't be tied to one js framework over the other. There's plenty of web components out there already like the time component (https://github.com/github/time-elements) I showed you before.
Have you decided what css framework we're going to stick with going forward?